منابع مشابه
Pancreatic cancer takes its Toll
Development of pancreatic ductal adenocarcinoma (PDAC) is known to be driven by a persistent inflammatory state, as oncogenic mutations alone are not sufficient for tumorigenesis. Toll-like receptors (TLRs), the pillars of the innate immune system, are highly expressed in the tumor microenvironment and on circulating leukocytes in PDAC. Contrasting results have reported antitumorigenic effects ...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2015
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3280